annie's picture
TitleOrganizing principles of pulvino-cortical functional coupling in humans.
Publication TypeJournal Article
Year of Publication2018
AuthorsArcaro, MJ, Pinsk, MA, Chen, J, Kastner, S
JournalNat Commun
Volume9
Issue1
Pagination5382
Date Published2018 Dec 19
ISSN2041-1723
Abstract

The pulvinar influences communication between cortical areas. We use fMRI to characterize the functional organization of the human pulvinar and its coupling with cortex. The ventral pulvinar is sensitive to spatial position and moment-to-moment transitions in visual statistics, but also differentiates visual categories such as faces and scenes. The dorsal pulvinar is modulated by spatial attention and is sensitive to the temporal structure of visual input. Cortical areas are functionally coupled with discrete pulvinar regions. The spatial organization of this coupling reflects the functional specializations and anatomical distances between cortical areas. The ventral pulvinar is functionally coupled with occipital-temporal cortices. The dorsal pulvinar is functionally coupled with frontal, parietal, and cingulate cortices, including the attention, default mode, and human-specific tool networks. These differences mirror the principles governing cortical organization of dorsal and ventral cortical visual streams. These results provide a functional framework for how the pulvinar facilitates and regulates cortical processing.

DOI10.1038/s41467-018-07725-6
Alternate JournalNat Commun
PubMed ID30568159
PubMed Central IDPMC6300667